MovDisordV3, Main, Exploration, bibRecord, 003016

Apolipoprotein E ε4 allele is associated with Parkinson disease risk in a Mexican Mestizo population

Identifieur interne : 003016 ( Main/Exploration ); précédent : 003015; suivant : 003017

Apolipoprotein E ε4 allele is associated with Parkinson disease risk in a Mexican Mestizo population

Auteurs : Marisol L Pez [Mexique] ; Jorge Guerrero [Mexique] ; Petra Yescas [Mexique] ; Marie-Catherine Boll [Mexique] ; Itziar Familiar [Mexique] ; Adriana Ochoa [Mexique] ; Astrid Rasmussen [Mexique] ; María Elisa Alonso [Mexique]

Source :

Movement Disorders [ 0885-3185 ] ; 2007-02-15.

RBID : ISTEX:1F26F976DA25D22D7F6FA08029AC30197ED4BF7B

Descripteurs français

Wicri :
- geographic : Mexique.

English descriptors

KwdEn :
- Age of Onset, Aged, Apolipoprotein E4 (genetics), Female, Gene Frequency, Genetic Predisposition to Disease, Genotype, Humans, Male, Mexico (epidemiology), Middle Aged, Parkinson Disease (epidemiology), Parkinson Disease (genetics), Parkinson disease, Risk, age at onset, apolipoprotein E.
MESH :
- chemical , genetics : Apolipoprotein E4.
- geographic , epidemiology : Mexico.
- epidemiology : Parkinson Disease.
- genetics : Parkinson Disease.
- Age of Onset, Aged, Female, Gene Frequency, Genetic Predisposition to Disease, Genotype, Humans, Male, Middle Aged, Risk.

Abstract

We investigated the association between apolipoprotein E (APOE) alleles and genotypes and Parkinson disease (PD) in 229 unrelated Mexican Mestizo PD patients and 229 controls. Results showed that both APOE‐ε4 allele and APOE ε4/ε3 genotype are associated with PD (OR = 1.736, P = 0.011; OR = 1.688, P = 0.019, respectively). Mean age at onset of PD was not associated to any APOE allele or genotype, but was significantly earlier in familial PD when compared to sporadic cases (P = 0.025). © 2006 Movement Disorder Society

Url:

https://api.istex.fr/document/1F26F976DA25D22D7F6FA08029AC30197ED4BF7B/fulltext/pdf

DOI: 10.1002/mds.21340

Affiliations:

Mexique

Le document en format XML

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<author><name sortKey="Yescas, Petra" sort="Yescas, Petra" uniqKey="Yescas P" first="Petra" last="Yescas">Petra Yescas</name>
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<author><name sortKey="Boll, Marie Atherine" sort="Boll, Marie Atherine" uniqKey="Boll M" first="Marie-Catherine" last="Boll">Marie-Catherine Boll</name>
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<author><name sortKey="Ochoa, Adriana" sort="Ochoa, Adriana" uniqKey="Ochoa A" first="Adriana" last="Ochoa">Adriana Ochoa</name>
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<term>Gene Frequency</term>
<term>Genetic Predisposition to Disease</term>
<term>Genotype</term>
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<term>Mexico (epidemiology)</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">We investigated the association between apolipoprotein E (APOE) alleles and genotypes and Parkinson disease (PD) in 229 unrelated Mexican Mestizo PD patients and 229 controls. Results showed that both APOE‐ε4 allele and APOE ε4/ε3 genotype are associated with PD (OR = 1.736, P = 0.011; OR = 1.688, P = 0.019, respectively). Mean age at onset of PD was not associated to any APOE allele or genotype, but was significantly earlier in familial PD when compared to sporadic cases (P = 0.025). © 2006 Movement Disorder Society</div>
</front>
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<tree><country name="Mexique"><noRegion><name sortKey="L Pez, Marisol" sort="L Pez, Marisol" uniqKey="L Pez M" first="Marisol" last="L Pez">Marisol L Pez</name>
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<name sortKey="Alonso, Maria Elisa" sort="Alonso, Maria Elisa" uniqKey="Alonso M" first="María Elisa" last="Alonso">María Elisa Alonso</name>
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<name sortKey="Familiar, Itziar" sort="Familiar, Itziar" uniqKey="Familiar I" first="Itziar" last="Familiar">Itziar Familiar</name>
<name sortKey="Guerrero, Jorge" sort="Guerrero, Jorge" uniqKey="Guerrero J" first="Jorge" last="Guerrero">Jorge Guerrero</name>
<name sortKey="Ochoa, Adriana" sort="Ochoa, Adriana" uniqKey="Ochoa A" first="Adriana" last="Ochoa">Adriana Ochoa</name>
<name sortKey="Rasmussen, Astrid" sort="Rasmussen, Astrid" uniqKey="Rasmussen A" first="Astrid" last="Rasmussen">Astrid Rasmussen</name>
<name sortKey="Yescas, Petra" sort="Yescas, Petra" uniqKey="Yescas P" first="Petra" last="Yescas">Petra Yescas</name>
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Movement Disorders (revue)

Apolipoprotein E ε4 allele is associated with Parkinson disease risk in a Mexican Mestizo population

Apolipoprotein E ε4 allele is associated with Parkinson disease risk in a Mexican Mestizo population

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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